2,3-dihydrobenzofuran-6-carboxylic acid

2,3-dihydrobenzofuran-6-carboxylic acid - Names and Identifiers

Name	2,3-dihydro-1-benzofuran-6-carboxylic acid
Synonyms	2,3-dihydrobenzofuran-6-carboxylic acid 6-Benzofurancarboxylic acid, 2,3-dihydro- 6-benzofurancarboxylic acid, 2,3-dihydro- 2,3-dihydro-1-benzofuran-6-carboxylic acid
CAS	301836-57-7
InChI	InChI=1/C9H8O3/c10-9(11)7-2-1-6-3-4-12-8(6)5-7/h1-2,5H,3-4H2,(H,10,11)

2,3-dihydrobenzofuran-6-carboxylic acid - Physico-chemical Properties

Molecular Formula	C9H8O3
Molar Mass	164.16
Density	1.344±0.06 g/cm3(Predicted)
Boling Point	322.8±31.0 °C(Predicted)
Flash Point	136°C
Vapor Presure	0.000112mmHg at 25°C
pKa	4.25±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.61

2,3-dihydrobenzofuran-6-carboxylic acid - Introduction

2. acid is an organic compound with the chemical formula C9H8O3.

Nature:
2, acid is a colorless crystalline solid with a special aromatic flavor. It is insoluble in water at room temperature, but soluble in organic solvents such as ethanol and dichloromethane.

Use:
2, acid plays an important role in drug synthesis. It can be used for the synthesis of other drug intermediates, and can also be used as the structural skeleton of drugs.

Method:
2. The synthesis of acid can be obtained by the reaction of benzyl alcohol and 2,3-dihydrofuran. First, benzyl alcohol and 2,3-dihydrofuran undergo an alcohol ether exchange reaction under alkaline conditions to produce 2-benzyl -2, 3-dihydrofuran. Then, 2-benzyl-2,3-dihydrofuran undergoes an acid hydrolysis reaction to give 2, acid.

Safety Information:
2, acid has no obvious danger under regular use. However, as an organic compound, it may have irritating effects on the skin, eyes and respiratory system, so care should be taken to avoid contact when using it. Wear appropriate personal protective equipment such as lab gloves and goggles when used in a laboratory environment. In addition, the compound should be stored and handled properly to avoid reaction with other chemicals, fire and high temperatures.

Last Update：2024-04-09 21:01:54